Sandy Hutchens Cancer Prevention

Merck, Eli Lilly and Pfizer make announcement

The three pharmaceutical giants announced a plan to create a not-for-profit company in Singapore that will help speed up research on new medicines to treat gastric and lung cancers, which have become prevalent in Asia.

the Asian Cancer Research Group

The company, which will be called the Asian Cancer Research Group, is one of the first examples of a collaboration among major drug companies to combine resources and expertise to rapidly increase the knowledge of a disease and the disease process.

Merck is headquartered in Readington, Pfizer in New York and Eli Lilly in Indianapolis.

Over the next two years, the three companies will work on creating an extensive pharmacogenomic cancer database. The database will consist of information taken from about 2,000 tissue samples from patients with lung and gastric cancer and will be made available to researchers around the world.

The data will be housed and shared with scientists at the Lilly Singapore Center, Eli Lilly’s drug research facility.

“Through its work and the subsequent sharing of information, the information, the Asian Cancer Research Group hopes to empower researchers, foster innovation and improve the prognosis and treatment of patients with cancer,’’ said Gary Gilliand, senior vice president and franchise head, oncology, Merck Research Laboratories.

Sage Bionetworks

The creation of the research group was inspired by the non-profit Seattle-based Sage Bionetworks, which was founded by Stephen Friend, who previously headed Merck’s cancer research efforts.

New Study Claims that 2 Sodas Per Week Increases Pancreatic Cancer Risk

Two soft drinks a week may double the risk of getting pancreatic cancer, according to a recent study.

The soda industry strongly disagreed with the study, calling it flawed and showing other research that did not find an association between soda drinking and pancreatic cancer.

”People who drank two or more soft drinks a week had an 87% increased risk – or nearly twice the risk – of pancreatic cancer compared to individuals consuming no soft drinks,” says study lead author Noel T. Mueller, MPH, a research associate at the Cancer Control Program at Georgetown University Medical Center, Washington, D.C.

Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research has published the study.

Cancer of the pancreas was found in over 40,000 people in America in 2009, according to American Cancer Society estimates, and about 35,000 deaths from the disease were expected. The pancreas lies beneath the stomach and creates the hormone insulin to balance blood sugar. It also produces juices with enzymes in order to break down fats and proteins.

Video on pancreatic cancer

Prior studies showed mixed conclusions as to the connection of of soft drinks boosts the risk of pancreatic cancer.

Mueller and his associates studied 60,524 men and women enrolled in a Singapore Chinese Health Study, which began in the early 1990’s, for up to 14 years, to observe their diet and whether they got cancer.

They asked all participants about food intake, including sodas and juices. Mueller says the researchers didn’t ask specifically about diet soda consumption, but that most of the soda drunk was regular or sweetened.

In Singapore at that time, Mueller says, there was very little intake of diet soda.

“We followed the participants for 14 plus years, keeping track of different cancers,” he tells WebMD.

They found 140 cases of pancreatic cancer and looked back to see if there was an association with sodas or juices.

The researchers divided the consumption of sodas and juices into three categories: none, less than two servings a week, or two or more servings a week.

Those who drank two or more a week — the average number was five — had the 87% increased risk, Mueller tells WebMD.

No link was found between juices and pancreatic cancer risk.

Why is there an association with soft drinks? Mueller says they are not certain. “What we believe is the sugar in the soft drinks is increasing the insulin level in the body, which we think contributes to pancreatic cancer cell growth. That increase in insulin is what may be leading to the development of the cancer.”

His team adjusted for other risk factors, such as advancing age, smoking, diabetes, and body mass index. It is well known that the risk for pancreatic cancer rises with age.

The use of screening test for cervical cancer

As it turns out BBC News has reported the use of screening tests other than smears may prevent of more deaths caused by cervical cancer. This is so for women who are over 35.

Italian researchers headed by Dr. Guglielmo Ronco of the Turin Centre for Cancer Prevention studied data on over 90,000 women over three and a half years. The findings were that women who have been tested for the human papillomavirus (HPV) suffered less cancers than women who were tested using the more common smear technique.

Testing for HPV can pick up early pre-cancerous alterations to cervical cells, which means that the correct treatment can be started at an early stage. The director of information at the Cancer Research UK,, Dr. Leslie Walker state that “we might be able to spot the warning signs even earlier and it might, in future, mean that women go for screening less often.”

The good news according to the research is that HPV testing does not require the same amount of testing. Once every five years will do whereas smears need to be done once every three years.

Good for women under the age of 35

Unfortunately this type of testing is not the best one for all women. Since HPV testing is generally more sensitive, it also tends to find problems that, when discovered in younger women, often correct themselves over time and are truly better left untreated. Therefore, the testing is not best suited for women under the age of 35 in order to avoid being over-treated.

We encourage you to read more on this.

Doctor Speaks About Cervical Cancer Screenings

Dr. Bernadine Healy speaks about ACOG’s new recommendations for less frequent pap smears to detect cervical cancer in this video.