Finding the right foods and nutrition supplements that help prevent cancer is a difficult aspect of research: often, when researchers think that they understand something, a newer study arrives that finds that the opposite is true.

Lung cancer was diagnosed 220,000 times last year and resulted in 160,000 fatalities. Researchers are searching for vitamins that help reduce cancer risk. Beta-carotene was once a contender as an anti-carcinogen. However in 2004, a major study found that in the case of smokers, beta-carotene supplements increased lung cancer risk.

With such reversals in their thinking, cancer researchers are careful to curb their enthusiasm over new studies that may offer hope in lung cancer prevention. However this week, there have been two new studies which have discovered very promising qualities to green tea and green vegetables.

Folic Acid and Phytochemicals

In one study which included over one thousand current or former smokers it was found that people whose diets had been high in folic acid, leafy-green vegetables and those currently taking multivitamins rich in phytochemicals (vitamins A, C, K, folate, carotenoids and lutein) showed lower levels of genetic changes causing lung cancer in smokers.

The second found that compared with Taiwanese smokers who drank at least one cup of green tea a day, smokers who did not drink green tea were almost thirteen times more likely to get lung cancer. Smokers who had genetic variations that put them at greater risk of developing lung cancer didn’t get quite as much protection from green tea as those who didn’t have those genetic variations. But they still benefited.

The polyphenols found in tea, and especially in green tea, have drawn lots of attention as potential cancer-blockers. This study was presented at a conference being held this week in Coronado, Calif., on lung cancer and its molecular origins. It’s sponsored by the American Assn. for Cancer Research.

The leafy-greens study, published in the journal Cancer Research, appeared online Tuesday. Officials of the National Cancer Institute, which funded the study, lauded the study as “well designed.” But in a statement, NCI’s biomarkers research group chief Sudhir Srivastava cautioned that more research would need to strengthen the evidence–even for leafy greens–before it could serve as the basis for dietary recommendations.

The Benefits of Leafy Greens for Lung Cancer

Eating a pomegranate everyday can help prevent breast cancer, new research reveals. American scientists are saying pomegranates contain chemical agents known as phytochemicals, which play an important role in the prevention of breast cancer.

Scientists at the City of Hope Cancer Research and Treatment Center in Duarte, California, have discovered that the fruit contains a large amount of the phytochemical called ellagitannins. The phytochemical has an inhibitory effect on the enzyme aromatase, which plays a pivotal role in making the hormone oestrogen, which in turn leads to most of the cases of breast cancer. Meanwhile, many patients who suffer from the breast cancer take medicines which are actually aromatase inhibitors.

The research which was published in the journal ‘Cancer Prevention Research’ highlights the fact that laboratory experiments that were carried out took into account around 10 compounds from the pomegranate and their effects were subsequently tested. Among the compounds which were taken into consideration, urolithin B was seen to be the most effective in preventing breast cancer.

However, researcher Shiuan Chen, who was intrinsically involved with the research, emphasized that the compounds did not turn out to be as effective as actual drugs due to which researchers have warned the patients against using the fruit as a replacement of the aromatase inhibitor medicines. At the same time, it has been implied that the results are not conclusive and further tests need to be carried out in order to confirm the findings. However, the findings are being considered to be significant as it might herald a new era in breast cancer treatment.

Read more: Pomegranates and Cancer.

All of us have the gift of laughter. Laughter itself is nature’s medicine. Our spirits are lifted and we feel happy. Laughter is contagious. It can bring human beings together in joy. It can also enable us to feel more alive.

Laughter therapy is the use of humor such as the Three Stooges on New Year’s to promote our health and well being. By employing our native physiological process of laughter we are relieved of our physical and emotional burdens.

Laughter Therapy Studies

A growing number of studies support the view that laughter has therapeutic value.

Humor has been used in medicine for millenia. Surgeons have used humor to distract their patients for centuries.The 20th century revealed a scientific study of the effect of humor on wellness. Norman Cousins is famous for promoting this in Anatomy of an Illness which looked at humour such as The Three Stooges and the Marx Brothers as healing balms for the soul. Cousins claims that he cured himself with laughter and vitamins.

Over the years, studies have explored the impact of laughter on our health. After testing study participants before and after a humorous event it was revealed that episodes of the Three Stooges helped to reduce pain, decrease stress hormones and boosted the patients immune systems.

Now more than ever before in history, people are turning to humour for healing. Medical journals are agreeing that laughter therapy help improve quality of life for those suffering from chronic illnesses. A lot of hospitals offer laughter therapy programs as an alternative treatment.

Laughter Heals

It certainly seems strange to turn to humour when faced such serious issues. Yet, laughter can be helpful in ways you might not have realized or imagined.

Laughter helps you with your own self esteem and the life flowing around you. When you are in a state of laughter, no thing is in your mind. Laughter also creates physical changes in your body. After laughter lasting only a few minutes, you will probably feel better for many hours.

When appended to conventional cancer treatments, laughter therapy helps the healing process.

Studies show that laughter therapy provides physical benefits:

• Boosting your immune and circulatory system
• Enhancing your oxygen intake
• Stimulating your heart and lungs
• Setting off the release of your endorphins
• Easing digestive problems
• Relieving pains
• Balancing your blood pressure
• Improving all your mental functions

Laughter is the best medicine, Three Stooges, Twighlight Zone Marathon, New Years 2010

A promising cancer drug, first discovered in a mushroom commonly used in Chinese medicine, could be made more effective thanks to researchers who have discovered how the drug works. The research is funded by the Biotechnology and Biological Sciences Research Council and was carried out at The University of Nottingham.

In research to be published in the Journal of Biological Chemistry, Dr Cornelia de Moor of The University of Nottingham and her team have investigated a drug called cordycepin, which was originally extracted from a rare kind of wild mushroom called cordyceps and is now prepared from a cultivated form.

Dr de Moor said: “Our discovery will open up the possibility of investigating the range of different cancers that could be treated with cordycepin. We have also developed a very effective method that can be used to test new, more efficient or more stable versions of the drug in the Petri dish. This is a great advantage as it will allow us to rule out any non-runners before anyone considers testing them in animals.”

Cordyceps is a strange parasitic mushroom that grows on caterpillars (see image). Properties attributed to cordyceps mushroom in Chinese medicine made it interesting to investigate and it has been studied for some time. In fact, the first scientific publication on cordycepin was in 1950. The problem was that although cordycepin was a promising drug, it was quickly degraded in the body. It can now be given with another drug to help combat this, but the side effects of the second drug are a limit to its potential use.

Dr de Moor continued: “Because of technical obstacles and people moving on to other subjects, it’s taken a long time to figure out exactly how cordycepin works on cells. With this knowledge, it will be possible to predict what types of cancers might be sensitive and what other cancer drugs it may effectively combine with. It could also lay the groundwork for the design of new cancer drugs that work on the same principle.”

The team has observed two effects on the cells: at a low dose cordycepin inhibits the uncontrolled growth and division of the cells and at high doses it stops cells from sticking together, which also inhibits growth. Both of these effects probably have the same underlying mechanism, which is that cordycepin interferes with how cells make proteins. At low doses cordycepin interferes with the production of mRNA, the molecule that gives instructions on how to assemble a protein. And at higher doses it has a direct impact on the making of proteins.

Learn about Herbs – Rhodiola and Cordyceps (video)

Ana Ripoll, Rector of Universitat Aut-noma de Barcelona (UAB), and Pedro Barato, President of “Organizaci-n Interprofesional del Aceite de Oliva Espa-ol”, signed a research agreement to carry out an in depth study on how the intake of olive oil can work towards preventing and fighting against breast cancer. The Multidisciplinary Group on Breast Cancer Research (GMECM), directed by Dr Eduard Escrich, lecturer of the Department of Cell Biology, Physiology and Immunology, will be working on this research project during the next five years. GMECM has demonstrated in previous researches that a moderate intake of virgin olive oil slows down the spreading of this cancer.

Researchers at GMECM aim to determine the possible activity of common components of the human diet with the objective of formulating scientific opinions on the health of the population or levels of risk, all within the field of breast cancer prevention. Among the results obtained until now researchers highlight the fact that a moderate intake of virgin olive oil can slow down the spreading of this cancer due to the action of mechanisms which counterattack the possible harmful effects of fats, while an excessive intake of seed oils has damaging effects.

In the study, which will begin this coming year, researchers will continue to study the effects olive oil can have on this type of cancer, with experimental studies and with human cell lines and samples. Among the research studies to be carried out, some of the most prominent focus on the effects fats and oils can have on mammary tumours, and especially those of extra virgin olive oil, and an analysis of the molecular changes found in these tumours in all of the genome and in the specific genes implicated in this pathology.

Olive oil lowers risk of breast cancer

Harvard researchers are finding an intriguing link between coffee and the prevention of an aggressive type of prostate cancer.

Prostate cancer kills 27,000 men annually. So this research comparing the history of thousands and thousands of men raises the possibility of a simple and effective prevention in this deadly disease.

The researchers discovered that men who drank six or more cups of coffee a day had a 60 percent lower risk developing the advanced form of the disease when compared to men who drank no coffee at all.

Even men who drank just one to three cups are showed a lower risk, about 20 percent, of developing the aggressive cancer.

Prostate cancer specialist Dr. Ihor Sawczuk, of Hackensack University Medical Center, says the researchers were not exactly sure what it is about the coffee that might affect the cancers. But he says it’s too early to recommend boosting coffee drinking to men, although one cup of coffee might be helpful.

“I think those that don’t drink coffee should consider perhaps a cup a day may help build up their immune system,” he said. “I think what we need to remember is there may be more to this story.”

And finding out more details will be the next job for researchers. Because one study is not enough for scientists, the findings will need to be confirmed.

But if coffee helps prevention, it’s a bonus for those who already drink it and a simple benefit for those who don’t.

Prostate cancer survivor Richard Williamson has made some already-proven lifestyle changes for his recovery. He’s lost 25 pounds, walks two miles daily and, because he doesn’t eat enough fruits and vegetables, now frequents a health food store near his home to get his vegetables in a drink he likes.

“I do my walk and then I stop there,” he said. “I do that three or four times a week.”

Other proven prevention habits include:

“Decrease the total amount of fat, taking good fat, for example, the omega-3,” Dr. Sawczuk said. “Tomatoes have lycopene, especially the skin of tomatoes. These are good substancse to ingest. Soy products, apples, perhaps even a glass of red wine.”

And now, maybe a cup of coffee or two. One way coffee might be working is that it’s known to help the body use insulin. And high insulin has already been proven to increase risk of prostate cancer.

Vitamin D is essential for promoting calcium absorption for bone and overall health in people. Low levels of vitamin D can lead to rickets in infants and children and the loss of bone density in adults.

More than 25 million adults in the United States have or are at risk of developing osteoporosis, a disease characterized by the loss of bone density that makes bones fragile and significantly increases the risk of fractures. When it comes to Osteoporosis, it’s a chicken and egg scenario: osteoporosis is most often associated with inadequate calcium intakes (generally less than 1,000-1,200 mg/day), but insufficient vitamin D contributes to osteoporosis by reducing the body’s calcium absorption.

While the evidence is far from conclusive, vitamin D may also prove to be an important protective nutrient in the prevention and treatment of cancer.

Video: Possible 75% cancer mortality reduction with Vitamin D

In a new study, researchers at the Moores Cancer Center and Department of Family and Preventive Medicine, UC San Diego used a complex computer prediction model to determine that intake of vitamin D3 and calcium would prevent 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer annually in the US and Canada. The researchers model also predicted that 75% of deaths from these cancers could be prevented with adequate intake of vitamin D3 and calcium. Dr. Cedric Garland, UCSD School of Medicine, lead researcher on the study discusses the implications of this finding and the proposed actions.

Although scientists are reluctant to endorse green tea as a cancer prevention method, evidence continues to grow regarding the chemically complex drink’s potential benefits – including results of a new randomized, controlled trial by researchers at University of Texas M. D. Anderson Cancer Center, which suggest it had some inhibiting effect in patients with a pre-malignant condition known as oral leukoplakia.

As reported in a report published online Nov 5 by Cancer Prevention Research(1), a team headed by Vassiliki Papadimitrakopoulo, MD, professor of medicine in M.D. Anderson’s Department of Thoracic/Head and Neck Medical Oncology, tested green tea extract taken orally for three months by 41 patients diagnosed with oral leukoplakia and therefore at high risk of developing oral cancer.

The patients were divided into cohorts taking either placebo or one of three different doses of green tea extract 500 mg/m2, 750 mg/m2 or 1,000 mg/m2 [mg/m2 refers to milligrams per meter squared of body mass – calculated by a formula using height and weight to reflect a person’s relative size].

The researchers assessed clinical response in oral pre-malignant lesions and found:

• 58.8% of patients at the highest doses displayed clinical response,

• Compared with 18.2% among those taking placebo.

They also observed:

• A trend toward improved histology [cell & tissue integrity],

• And a trend towards improvement in a handful of biomarkers that may be important in predicting cancer development.

Patients were followed for 27.5 months and at the end of the study period, 15 developed oral cancer.

• Although there was no difference in oral cancer development overall between those who took green tea and those who did not,

• Patients who presented with mild to moderate dysplasia [abnormal cell growth] had a longer time to develop oral cancer if they took green tea extract.

Although encouraged by the results, Dr. Papadimitrakopoulo cautioned against any recommendations that green tea could definitely prevent cancer.

“This is a phase II study with a very limited number of patients who took what would be the equivalent of drinking eight to 10 cups of green tea every single day,” she said. “We cannot with certainty claim prevention benefits from a trial this size.”

Dong Shin, MD, (professor of hematology and medical oncology at Emory School of Medicine, and a Cancer Prevention Research editorial board member) agreed, but said this trial is certainly a step in the right direction. “A clinical trial with a natural compound is no easy task, and these researchers have accomplished that,” Dr. Shin stated in a companion article commenting on the trial(2). “The lack of toxicity is also important because often when you give supplements at higher doses than what would occur naturally, you induce nausea and vomiting. That did not happen in this trial.”

Neither researcher had a reason why patients concerned about cancer should not drink green tea, but they cautioned against relying on the beverage to definitively reduce their risk of cancer.

“The goal of this kind of research is to determine whether or not these supplements have long-term prevention effects,” said Dr. Papadimitrakopoulou. “More research – including studies in which individuals at high risk are exposed to these supplements for longer time period – is still needed to answer that sort of question.”

Tobacco

This is the single largest preventable cause of cancer in the world. It causes over 80% of all lung cancer deaths, and 30% of all cancer deaths in the third world. This includes deaths from cancer of the oral cavity, larynx, oesophagus and stomach. A comprehensive program which would include a stop to tobacco advertising, increased taxation on tobacco products, and stop smoking programs can greatly reduce the use of tobacco in many countries. The World Health Organization Framework Convention on Tobacco Control adopted measures in May 2003, aims to curb tobacco-related deaths and disease. We are looking for updates on their progress.

Diet

Changes in diet is another critical action to take to prevent and control cancer. There are know links between obesity and many types of cancer such as oesophagus, colorectum, breast, endometrium and kidney. Diets high in fruits and vegetables have a preventative effect against a great number of cancers. On the other hand, consumption of red and preserved meat is connected with an increased risk of colorectal cancer.Healthy eating habits which ameliorate the development of diet-related cancers have the added benefit of lowering the potential for cardiovascular disease.

Exercise

Regular physical exercise along with a healthy body weight and healthy diet, will greatly reduce the chances of cancer. National policies and programs have been implemented in some countries which raise awareness and reduce exposure to cancer risk factors. To ensure that citizens are provided with the information and the tools they need to adopt healthy lifestyles governments may play a large role.

Preventing Disease

Infectious agents are responsible for almost one quarter of cancer deaths in the third world and 1 in 20 in industrialized countries. Viral hepatitis B and C can cause liver cancer; human papilloma virus infection can cause cancer of the cervix; the bacterium Helicobacter pylori can greatly increase the risk of stomach cancer. In some countries the parasitic infection schistosomiasis increases the risk of bladder cancer and in other countries the liver fluke increases the risk of cholangiocarcinoma to do with the bile ducts system. Preventive measures include vaccination and prevention of infection and infestation.

Radiation

Exposure to radiation is well known to cause some cancers. Solar ultraviolet radiation can raise the risk of all types of skin cancer. Avoiding excessive exposure, use of sunscreen and protective clothing are important preventive activities.

Asbestos

On the subject of home and workplace safety, asbestos must be looked at because it can cause lung cancer. Also aniline dyes have been linked to bladder cancer. Benzene has been linked to leukemia. The prevention of certain occupational and environmental exposure to these and other chemicals are important steps to take in preventing cancer.

Smile For Cancer Prevention video

After working initially with human cancer cell lines, Ines Diaz-Laviada and colleagues from the University of Alcala in Madrid also tested one compound on mice and discovered it produced a significant reduction in tumor growth. Their research, published in the British Journal of Cancer, underlines the growing interest in the medical use of active chemicals called cannabinoids, which are found in marijuana.

Experts, however, stressed that the research was still exploratory and many more years of testing would be needed to work out how to apply the findings to the treatment of cancer in humans.

“This is interesting research which opens a new avenue to explore potential drug targets but it is at a very early stage,” said Lesley Walker, director of cancer information at Cancer Research UK, which owns the journal. “It absolutely isn’t the case that men might be able to fight prostate cancer by smoking cannabis,” she added

The cannabinoids tested by the Spanish team are thought to work against prostate cancer because they block a receptor, or molecular doorway, on the surface of tumour cells. This stops them from dividing. In effect, the cancer cell receptors can recognize and “talk to” chemicals found in cannabis, said Diaz-Laviada.

“These chemicals can stop the division and growth of prostate cancer cells and could become a target for new research into potential drugs to treat prostate cancer,” she said. Her team’s work with two cannabinoids — called methanandamide and JWH-015 — is the first demonstration that such cannabis chemicals prevent cancer cells from multiplying.

Some drug companies are already exploring the possibilities of cannabinoids in cancer, including British-based cannabis medicine specialist GW Pharmaceuticals. It is collaborating with Japan’s Otsuka on early-stage research into using cannabis extracts to tackle prostate cancer — the most commonly diagnosed cancer in men — as well as breast and brain cancer.

GW has already developed an under-the-tongue spray called Sativex for the relief of some of the symptoms of multiple sclerosis, which it plans to market in Europe with Bayer and Almirall. Other attempts to exploit the cannibinoid system have met with mixed success. Sanofi-Aventis was forced to withdraw its weight-loss drug Acomplia from the market last year because of links to mental disorders.

Cruel Treatment of Medical Marijuana Patient video posted by Sandy Hutchens Cancer Prevention